Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GALR2 | O43603 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23577752 | 1.00 | LMNA (0.43) | LMNATP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL23578095 | 0.85 | ALDH1A1 (0.43) | LMNATP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL30034889 | 0.85 | ALDH1A1 (0.43) | LMNATP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL23590999 | 0.80 | SMN1; SMN2 (0.40) | LMNATP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL30036541 | 0.78 | KMT2A (0.38) | LMNATP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL23577722 | 0.78 | KMT2A (0.38) | LMNATP53SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL30183695 | 0.76 | LMNA (0.47) | LMNATP53MAPTALDH1A1KDM4E | |
| SCHEMBL23577635 | 0.76 | LMNA (0.47) | LMNATP53ALDH1A1KDM4ECA12 | |
| SCHEMBL23577953 | 0.76 | LMNA (0.47) | LMNATP53MAPTALDH1A1KDM4E | |
| SCHEMBL30183917 | 0.76 | LMNA (0.47) | LMNATP53ALDH1A1KDM4ECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605476-A | Substituted tricyclic compounds | 鲁宾有限公司（IN） | 2023-01-13 | — | — | CN | disclosed |