SCHEMBL30184205

SCHEMBL30184205

CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)O)[C@@H](C)O)C(C)C

nearest known ligand 0.61

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 3/20 0.61
▸ OPRD1 P41143 3/20 0.61
▸ OPRK1 P41145 1/20 0.61
▸ TFPI P10646 1/20 0.60
▸ IL23R Q5VWK5 9/20 0.59
▸ KEAP1 Q14145 1/20 0.55
▸ NPY4R P50391 6/20 0.54
▸ NPY1R P25929 5/20 0.54
▸ NPY2R P49146 5/20 0.54
▸ NPY5R Q15761 5/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30184327 0.93 TFPI (0.60) OPRM1OPRD1OPRK1TFPIIL23R
SCHEMBL30865075 0.93 TFPI (0.60) OPRM1OPRD1OPRK1TFPIIL23R
SCHEMBL30865068 0.92 TFPI (0.58) OPRM1OPRD1OPRK1TFPIIL23R
SCHEMBL30865071 0.92 TFPI (0.61) OPRM1OPRD1OPRK1TFPIIL23R
SCHEMBL30184264 0.91 TFPI (0.62) TFPINPY4RNPY1RNPY2RNPY5R
SCHEMBL30880902 0.89 OPRM1 (0.63) OPRM1OPRD1OPRK1TFPIIL23R
SCHEMBL29470903 0.88 TFPI (0.64) OPRM1OPRD1OPRK1TFPI
Dynorphin B SCHEMBL30415641 0.88 TFPI (0.65) OPRM1OPRD1OPRK1TFPIIL23R
SCHEMBL31145953 0.87 TFPI (0.59) OPRM1OPRD1OPRK1TFPIIL23R
SCHEMBL30865074 0.87 NPY4R (0.60) TFPIIL23RNPY4RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12551537-B2 Methods and compositions for the treatment and prevention of type 1 diabetes DR. MARY MORRIS & ASSOCIATES, LLC (US) 2026-02-17 — — US disclosed
US-20230018324-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF TYPE 1 DIABETES DR. MARY MORRIS & ASSOCIATES, LLC (US) 2023-01-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12551537-B2 Methods and compositions for the treatment and prevention of type 1 diabetes IAPP, GLP1R, SLC5A1 OPRM1 4593/4885OPRD1 4246/4885OPRK1 4720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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