SCHEMBL30184327

SCHEMBL30184327

CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)C(C)C

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.60
▸ NPY4R P50391 14/20 0.56
▸ NPY1R P25929 9/20 0.56
▸ NPY5R Q15761 8/20 0.56
▸ NPY2R P49146 5/20 0.56
▸ IL23R Q5VWK5 2/20 0.55
▸ OPRM1 P35372 1/20 0.55
▸ OPRD1 P41143 1/20 0.55
▸ OPRK1 P41145 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30865075 1.00 TFPI (0.60) TFPINPY4RNPY1RNPY5RNPY2R
SCHEMBL30865068 0.99 TFPI (0.58) TFPINPY4RNPY1RNPY5RNPY2R
SCHEMBL30865071 0.96 TFPI (0.61) TFPINPY4RNPY1RNPY5RNPY2R
SCHEMBL30184264 0.95 TFPI (0.62) TFPINPY4RNPY1RNPY5RNPY2R
SCHEMBL30184205 0.93 OPRM1 (0.61) TFPINPY4RNPY1RNPY5RNPY2R
SCHEMBL13912288 0.92 TFPI (0.61) TFPIIL23R
SCHEMBL13342836 0.92 TFPI (0.61) TFPIIL23R
SCHEMBL2881677 0.92 TFPI (0.61) TFPIIL23R
SCHEMBL12359225 0.92 TFPI (0.61) TFPIIL23R
SCHEMBL16015184 0.92 TFPI (0.61) TFPIIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12551537-B2 Methods and compositions for the treatment and prevention of type 1 diabetes DR. MARY MORRIS & ASSOCIATES, LLC (US) 2026-02-17 — — US disclosed
US-20230018324-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF TYPE 1 DIABETES DR. MARY MORRIS & ASSOCIATES, LLC (US) 2023-01-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12551537-B2 Methods and compositions for the treatment and prevention of type 1 diabetes IAPP, GLP1R, SLC5A1 TFPI 330/4885NPY4R 329/4885NPY1R 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback