Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.50 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26172231 | 0.81 | HTR6 (0.53) | HTR6ALDH1A1KCNQ3KCNQ2APOBEC3A | |
| SCHEMBL405686 | 0.79 | HTR6 (0.52) | HTR6ALDH1A1SMN1; SMN2 | |
| SCHEMBL29987490 | 0.77 | PDE2A (0.42) | HTR6MEN1KMT2AALDH1A1KCNQ3 | |
| SCHEMBL25261273 | 0.76 | KCNQ3 (0.43) | HTR6MEN1KMT2AALDH1A1KCNQ3 | |
| SCHEMBL16619547 | 0.74 | PIK3CG (0.45) | APOBEC3AAPOBEC3GPIK3CDPIK3CAPIK3CB | |
| SCHEMBL3714513 | 0.74 | PIK3CG (0.51) | HTR6MEN1KMT2AALDH1A1APOBEC3A | |
| SCHEMBL23728529 | 0.74 | APOBEC3A (0.45) | HTR6MEN1KMT2AALDH1A1GAA | |
| SCHEMBL18208430 | 0.73 | PIK3CG (0.44) | APOBEC3AAPOBEC3GPIK3CDPIK3CAPIK3CB | |
| SCHEMBL29939968 | 0.72 | HTR6 (0.43) | DHODHHTR6MEN1KMT2AALDH1A1 | |
| SCHEMBL943447 | 0.72 | KCNQ3 (0.41) | HTR6ALDH1A1KCNQ3KCNQ2APOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219978-A1 | COMPOUND HAVING MACROCYCLIC STRUCTURE AND USE THEREOF | SCINNOHUB PHARMACEUTICAL CO., LTD (CN) | 2023-07-13 | — | — | US | disclosed |
| EP-4163283-A1 | COMPOUND HAVING MACROCYCLIC STRUCTURE AND USE THEREOF | Scinnohub Pharmaceutical Co., Ltd (CN) | 2023-04-12 | — | — | EP | disclosed |
| CN-113754682-B | Compound having macrocyclic structure and use thereof | 赛诺哈勃药业（成都）有限公司 | 2023-01-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219978-A1 | COMPOUND HAVING MACROCYCLIC STRUCTURE AND USE THEREOF | BTK, SRC, YES1 | DHODH 4267/4885HTR6 2960/4885MEN1 306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.