Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 8/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 8/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26172231 | 0.80 | HTR6 (0.53) | KCNQ3KCNQ2APOBEC3AAPOBEC3GALDH1A1 | |
| SCHEMBL26247268 | 0.77 | APOBEC3A (0.41) | KCNQ3KCNQ2APOBEC3AAPOBEC3GALDH1A1 | |
| SCHEMBL29987490 | 0.76 | PDE2A (0.42) | KCNQ3KCNQ2APOBEC3AAPOBEC3GALDH1A1 | |
| SCHEMBL30184444 | 0.76 | DHODH (0.50) | KCNQ3KCNQ2APOBEC3AAPOBEC3GALDH1A1 | |
| SCHEMBL16619547 | 0.73 | PIK3CG (0.45) | APOBEC3AAPOBEC3G | |
| SCHEMBL23728529 | 0.73 | APOBEC3A (0.45) | KCNQ3KCNQ2APOBEC3AAPOBEC3GALDH1A1 | |
| SCHEMBL3714513 | 0.73 | PIK3CG (0.51) | APOBEC3AAPOBEC3GALDH1A1L3MBTL1HPGD | |
| SCHEMBL405686 | 0.72 | HTR6 (0.52) | ALDH1A1HPGDHTR6SMN1; SMN2 | |
| SCHEMBL18208430 | 0.72 | PIK3CG (0.44) | APOBEC3AAPOBEC3G | |
| SCHEMBL22102917 | 0.71 | KCNQ3 (0.36) | KCNQ3KCNQ2ALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023096850-A1 | PHOSPHOINOSITIDE 3 KINASE GAMMA INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | GEODE THERAPEUTICS INC. (US) | 2023-06-01 | — | — | WO | disclosed |
| WO-2023096850-A1 | PHOSPHOINOSITIDE 3 KINASE GAMMA INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | GEODE THERAPEUTICS INC. (US) | 2023-06-01 | — | — | WO | disclosed |