Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.62 |
| ▸ | RORC | P51449 | 10/20 | 0.55 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | JAK1 | P23458 | 1/20 | 0.51 |
| ▸ | TYK2 | P29597 | 1/20 | 0.51 |
| ▸ | JAK3 | P52333 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30185534 | 0.84 | RORC (0.57) | KIF11CYP2C9RORC | |
| SCHEMBL30185518 | 0.80 | KIF11 (0.47) | KIF11CYP2C9RORC | |
| SCHEMBL13983304 | 0.79 | KIF11 (0.56) | KIF11CYP2C9RORCJAK2JAK1 | |
| SCHEMBL13982856 | 0.78 | KIF11 (0.64) | KIF11CYP2C9JAK2JAK1TYK2 | |
| SCHEMBL13154896 | 0.75 | KIF11 (1.00) | KIF11CYP2C9 | |
| SCHEMBL19360323 | 0.73 | RORC (0.76) | RORC | |
| SCHEMBL30185508 | 0.72 | RORC (0.58) | KIF11CYP2C9RORC | |
| SCHEMBL13982828 | 0.72 | KIF11 (0.57) | KIF11CYP2C9JAK2JAK1TYK2 | |
| SCHEMBL19360483 | 0.72 | RORC (0.87) | RORC | |
| SCHEMBL13982732 | 0.72 | KIF11 (0.79) | KIF11CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759541-B | Indole-like derivatives and uses thereof | 复旦大学 | 2023-03-17 | — | — | CN | disclosed |