SCHEMBL30185523

SCHEMBL30185523

CCS(=O)(=O)c1ccc(Cc2cc3cc(C(N)=O)ccc3n2Cc2ccc(OC(C)C)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RORC P51449 19/20 0.51
PARP10 Q53GL7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30185525 0.86 RORC (0.48) RORC
SCHEMBL30185532 0.86 RORC (0.50) RORC
SCHEMBL30185498 0.86 RORC (0.47) RORC
SCHEMBL30185501 0.84 RORC (0.47) RORC
SCHEMBL30185535 0.83 RORC (0.59) RORC
SCHEMBL30185503 0.83 RORC (0.46) RORC
SCHEMBL30185505 0.79 RORC (0.59) RORC
SCHEMBL30185534 0.77 RORC (0.57) RORC
SCHEMBL30185508 0.77 RORC (0.58) RORC
SCHEMBL30185519 0.75 RORC (0.58) RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112759541-B Indole-like derivatives and uses thereof 复旦大学 2023-03-17 CN disclosed