Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28580014 | 1.00 | HDAC6 (0.52) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL30185536 | 0.87 | PLAU (0.52) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL28566459 | 0.87 | PLAU (0.52) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL28576841 | 0.85 | SLC22A12 (0.50) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL3109875 | 0.84 | HDAC6 (0.61) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL6086357 | 0.82 | HDAC6 (0.65) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL30185520 | 0.82 | HDAC6 (0.65) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL13699049 | 0.82 | KDM4E (0.55) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL5881976 | 0.81 | PLAU (0.57) | HDAC6HDAC8HDAC11HDAC3HDAC1 | |
| SCHEMBL28582440 | 0.80 | HDAC6 (0.78) | HDAC6HDAC8HDAC11HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759541-B | Indole-like derivatives and uses thereof | 复旦大学 | 2023-03-17 | — | — | CN | disclosed |