Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 6/20 | 0.32 |
| ▸ | HRH2 | P25021 | 3/20 | 0.31 |
| ▸ | HRH1 | P35367 | 3/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29099605 | 1.00 | GPR52 (0.32) | GPR52HRH2HRH1HRH4HRH3 | |
| SCHEMBL30185551 | 0.82 | TSHR (0.32) | GPR52NPC1ALDH1A1MAPTHPGD | |
| SCHEMBL30185591 | 0.77 | HRH2 (0.36) | GPR52HRH2HRH1HRH4HRH3 | |
| SCHEMBL29099535 | 0.77 | HRH2 (0.36) | GPR52HRH2HRH1HRH4HRH3 | |
| SCHEMBL3085308 | 0.72 | PIK3CD (0.52) | NPC1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL24023265 | 0.71 | PIK3CA (0.31) | HRH2HRH1HRH4HRH3PIK3CA | |
| SCHEMBL24023393 | 0.71 | PIK3CA (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGPI4KB | |
| SCHEMBL24023268 | 0.70 | MEN1 (0.33) | NPC1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL24023338 | 0.68 | XIAP (0.34) | NPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL24023335 | 0.68 | PIK3CA (0.41) | ALDH1A1MAPTRAB9ASMN1; SMN2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611883-B | PI3K alpha inhibitor with double-ring structure, and preparation method and application thereof | 生物岛实验室 | 2025-03-28 | — | — | CN | disclosed |
| CN-115611883-A | PI3K alpha inhibitor with bicyclic structure and preparation method and application thereof | 生物岛实验室 | 2023-01-17 | — | — | CN | disclosed |