SCHEMBL30186403

SCHEMBL30186403

CSCC[C@H](NC(=O)[C@@H](N)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ DPP3 Q9NY33 1/20 0.54
▸ ACE P12821 4/20 0.53
▸ F2 P00734 1/20 0.53
▸ OPRM1 P35372 5/20 0.53
▸ OPRD1 P41143 4/20 0.53
▸ APLNR P35414 1/20 0.50
▸ SLC6A2 P23975 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29824884 0.85 F2 (0.55) ACEF2OPRM1OPRD1APLNR
SCHEMBL31433252 0.85 GRB2 (0.50) DPP3ACEF2
SCHEMBL31717948 0.85 OPRM1 (0.56) DPP3OPRM1OPRD1SLC6A2
SCHEMBL30543190 0.85 F2 (0.61) ACEF2OPRM1OPRD1APLNR
SCHEMBL31433238 0.84 GRB2 (0.51) DPP3ACEF2OPRM1
SCHEMBL30512720 0.84 APLNR (0.53) F2OPRM1OPRD1APLNR
SCHEMBL31324068 0.83 DPP3 (0.52) DPP3F2SLC6A2
SCHEMBL31511422 0.83 APLNR (0.55) DPP3ACEF2OPRM1OPRD1
SCHEMBL31505799 0.83 F2 (0.58) ACEF2OPRM1OPRD1SLC6A2
SCHEMBL31362693 0.82 OPRM1 (0.55) ACEF2OPRM1OPRD1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024211447-A1 TP508 MRNAS CHRYSALIS BIOTHERAPEUTICS (US) 2024-10-10 — — WO disclosed
US-20230165943-A1 TP508 ACUTE THERAPY FOR PATIENTS WITH RESPIRATORY VIRUS INFECTION CHRYSALIS BIOTHERAPEUTICS, INC. 2023-06-01 — — US disclosed
EP-4132948-A1 TP508 ACUTE THERAPY FOR PATIENTS WITH RESPIRATORY VIRUS INFECTION Chrysalis Biotherapeutics (US) 2023-02-15 — — EP disclosed
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