SCHEMBL30186405

C[C@H](N)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	OPRD1	P41143	7/20	0.59

▸	OPRM1	P35372	5/20	0.59

▸	NTSR1	P30989	5/20	0.56

▸	F2	P00734	1/20	0.54

▸	NTSR2	O95665	1/20	0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30186436	0.88	CXCR4 (0.58)	—
SCHEMBL30607473	0.88	NPY2R (0.63)	—
SCHEMBL30802597	0.87	NTSR1 (0.60)	OPRM1NTSR1NTSR2
SCHEMBL30495628	0.87	OPRD1 (0.61)	OPRD1OPRM1
SCHEMBL30512571	0.87	OPRD1 (0.61)	OPRD1OPRM1NTSR1F2NTSR2
SCHEMBL30512664	0.86	OPRD1 (0.62)	OPRD1OPRM1NTSR1
SCHEMBL29596671	0.86	GRB2 (0.48)	OPRD1OPRM1NTSR1F2NTSR2
SCHEMBL30932399	0.86	CALCRL (0.55)	OPRD1OPRM1F2
SCHEMBL29714014	0.85	NTSR1 (0.64)	OPRM1NTSR1NTSR2
SCHEMBL30444236	0.85	SLC6A2 (0.62)	OPRD1OPRM1NTSR1F2NTSR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024211447-A1	TP508 MRNAS	CHRYSALIS BIOTHERAPEUTICS (US)	2024-10-10	—	—	WO	disclosed
US-20230165943-A1	TP508 ACUTE THERAPY FOR PATIENTS WITH RESPIRATORY VIRUS INFECTION	CHRYSALIS BIOTHERAPEUTICS, INC.	2023-06-01	—	—	US	disclosed
EP-4132948-A1	TP508 ACUTE THERAPY FOR PATIENTS WITH RESPIRATORY VIRUS INFECTION	Chrysalis Biotherapeutics (US)	2023-02-15	—	—	EP	disclosed