Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19642605 | 0.82 | MAPT (0.42) | ALDH1A1TSHRMDM2RAB9AMEN1 | |
| SCHEMBL19642232 | 0.80 | MAPT (0.63) | ALDH1A1MEN1KMT2AMAPTHDAC3 | |
| SCHEMBL9547932 | 0.77 | KMT2A (0.57) | ALDH1A1RAB9AALOX15HTTMEN1 | |
| SCHEMBL19642632 | 0.76 | KMT2A (0.65) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL19642671 | 0.76 | KMT2A (0.65) | ALDH1A1TSHRRAB9AMEN1KMT2A | |
| SCHEMBL2865544 | 0.76 | MAPT (0.65) | ALDH1A1MEN1KMT2AMAPTHDAC1 | |
| SCHEMBL11366024 | 0.73 | L3MBTL1 (0.61) | ALDH1A1TSHRMEN1KMT2AMAPT | |
| SCHEMBL19642631 | 0.73 | ATM (0.54) | ALDH1A1TSHRMDM2ATMRAB9A | |
| SCHEMBL5804124 | 0.73 | HDAC3 (0.56) | ALDH1A1TSHRMDM2ATMRAB9A | |
| SCHEMBL20491355 | 0.73 | ALOX15 (0.56) | ALDH1A1TSHRMDM2ATMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109863140-B | 3-oxo-2, 6-diphenyl-2, 3-dihydropyridazine-4-carboxamide | 拜耳医药股份有限公司 | 2023-02-21 | — | — | CN | disclosed |