Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | DHFR | P00374 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CTSC | P53634 | 1/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 2/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702197 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2HTTNPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL13518567 | 0.99 | SMN1; SMN2 (0.57) | SMN1; SMN2HTTNPC1RAB9AMEN1 | |
| SCHEMBL1702113 | 0.85 | IGF1R (0.61) | SMN1; SMN2HTTNPC1RAB9AMEN1 | |
| SCHEMBL1702887 | 0.81 | PDGFRB (0.62) | SMN1; SMN2NPC1RAB9AMEN1MAPT | |
| SCHEMBL1705284 | 0.81 | DHFR (0.54) | SMN1; SMN2HTTNPC1RAB9AMEN1 | |
| SCHEMBL1702586 | 0.80 | RAB9A (0.61) | SMN1; SMN2HTTNPC1RAB9AMEN1 | |
| SCHEMBL31098987 | 0.80 | RAB9A (0.61) | SMN1; SMN2HTTNPC1RAB9AMEN1 | |
| SCHEMBL1702296 | 0.80 | SCN9A (0.52) | SMN1; SMN2NPC1RAB9AMEN1MAPT | |
| SCHEMBL30764813 | 0.79 | NPC1 (0.55) | SMN1; SMN2HTTNPC1RAB9AMEN1 | |
| SCHEMBL21617086 | 0.79 | NPC1 (0.55) | SMN1; SMN2HTTNPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3645029-B1 | TREATMENTS TO ELIMINATE HIV RESERVOIRS AND REDUCE VIRAL LOAD | PASTEUR INSTITUT (FR) | 2023-01-18 | — | — | EP | claimed |