SCHEMBL30187484

SCHEMBL30187484

CCCCCCCCS(=O)(=O)Cc1ccc(O)c(CS(=O)(=O)CCCCCCCC)c1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 2/20 0.41
CA2 P00918 1/20 0.41
ESR1 P03372 4/20 0.41
ESR2 Q92731 4/20 0.41
SERPINE1 P05121 1/20 0.40
BACE1 P56817 1/20 0.40
TRPV1 Q8NER1 2/20 0.39
PPARA Q07869 1/20 0.38
S1PR2 O95136 1/20 0.38
S1PR1 P21453 1/20 0.38
S1PR3 Q99500 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28306851 0.80 MGLL (0.50) KAT8CA2ESR1ESR2PPARA
SCHEMBL28481982 0.80 ESR1 (0.56) CA2ESR1ESR2
SCHEMBL9353934 0.79 KDM4E (0.46) KAT8CA2ESR1ESR2TRPV1
SCHEMBL28878377 0.78 SHBG (0.38) CA2ESR1ESR2
SCHEMBL28065439 0.78 SHBG (0.38) CA2ESR1ESR2
SCHEMBL27779650 0.77 KAT8 (0.55) KAT8CA2ESR1BACE1PPARA
SCHEMBL10449694 0.77 KAT8 (0.55) KAT8CA2ESR1BACE1PPARA
SCHEMBL28865268 0.77 TYR (0.49) CA2ESR1ESR2SERPINE1
SCHEMBL10449692 0.75 KAT8 (0.54) KAT8CA2ESR1BACE1PPARA
SCHEMBL10449691 0.75 KAT8 (0.54) KAT8CA2ESR1BACE1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112955332-B Amino silyl functionalized conjugated dienes, their preparation and use in the manufacture of rubber 西索斯公司 2023-02-21 CN disclosed