Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | CASP7 | P55210 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28059768 | 1.00 | L3MBTL1 (0.49) | L3MBTL1NCOA1NCOA3PPARGNCOA2 | |
| SCHEMBL30343916 | 0.84 | IMPDH2 (0.47) | L3MBTL1NCOA1NCOA3PPARGNCOA2 | |
| SCHEMBL25156188 | 0.84 | IMPDH2 (0.47) | L3MBTL1NCOA1NCOA3PPARGNCOA2 | |
| SCHEMBL8583508 | 0.82 | CYP1A2 (0.50) | L3MBTL1NCOA1NCOA3PPARGNCOA2 | |
| SCHEMBL29176679 | 0.81 | CYP1A2 (0.44) | L3MBTL1NCOA1NCOA3PPARGNCOA2 | |
| SCHEMBL30344410 | 0.78 | DYRK1A (0.55) | L3MBTL1NCOA1NCOA3PPARGNCOA2 | |
| SCHEMBL25155913 | 0.78 | DYRK1A (0.55) | L3MBTL1NCOA1NCOA3PPARGNCOA2 | |
| SCHEMBL9560109 | 0.78 | MAOB (0.57) | L3MBTL1NCOA1NCOA3PPARGNCOA2 | |
| SCHEMBL27626481 | 0.77 | NQO1 (0.49) | L3MBTL1NCOA1NCOA3PPARGNCOA2 | |
| SCHEMBL19305540 | 0.76 | L3MBTL1 (0.42) | L3MBTL1NCOA1NCOA3PPARGNCOA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110240586-B | 2,3-dihydro-1H-benzo [ f ] chroman-2-amine derivatives and their preparation | 山东百极地长制药有限公司 | 2023-01-24 | — | — | CN | disclosed |