Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL831575 | 1.00 | KDM4E (0.47) | KDM4EHSD17B10HPGDALDH1A1LMNA | |
| SCHEMBL30147627 | 0.82 | ALOX15 (0.46) | KDM4EALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL831147 | 0.79 | KDM4E (0.54) | KDM4EHSD17B10HPGDALDH1A1LMNA | |
| SCHEMBL30104780 | 0.79 | KDM4E (0.54) | KDM4EHSD17B10HPGDALDH1A1LMNA | |
| SCHEMBL30189257 | 0.79 | KDM4E (0.56) | KDM4EHSD17B10HPGDALDH1A1LMNA | |
| SCHEMBL29301419 | 0.79 | KDM4E (0.56) | KDM4EHSD17B10HPGDALDH1A1LMNA | |
| SCHEMBL1100416 | 0.77 | CHRM1 (0.43) | KDM4EHSD17B10APEX1PIN1SMN1; SMN2 | |
| SCHEMBL14972759 | 0.76 | HSD17B10 (0.41) | KDM4EHSD17B10HPGDALDH1A1LMNA | |
| SCHEMBL25219154 | 0.76 | PIN1 (0.56) | KDM4EHSD17B10HPGDALDH1A1LMNA | |
| SCHEMBL2105708 | 0.76 | SMAD3 (0.49) | KDM4EHSD17B10HPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396485-A | PARP7 inhibitors | 轩竹生物科技股份有限公司 | 2024-01-12 | — | — | CN | disclosed |
| EP-4149945-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2023-03-22 | — | — | EP | disclosed |