Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.56 |
| ▸ | F3 | P13726 | 1/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1203070 | 1.00 | F7 (0.56) | F7F3GPR35SMAD3HPGD | |
| SCHEMBL4721594 | 0.88 | CHEK1 (0.44) | F7F3GPR35SMAD3HPGD | |
| SCHEMBL30189371 | 0.86 | GPR35 (0.51) | F7F3GPR35SMAD3HPGD | |
| SCHEMBL1824752 | 0.86 | GPR35 (0.51) | F7F3GPR35SMAD3HPGD | |
| Hydrochloric Acid SCHEMBL4400086 | 0.86 | CHEK1 (0.43) | F7F3GPR35SMAD3HPGD | |
| SCHEMBL13271409 | 0.85 | CCNC (0.44) | F7F3GPR35LMNAPYGL | |
| SCHEMBL13271671 | 0.85 | CHEK1 (0.43) | F7F3GPR35PIN1PYGL | |
| SCHEMBL4268891 | 0.82 | MEN1 (0.63) | F7F3HPGDKDM4EHSD17B10 | |
| SCHEMBL2106881 | 0.81 | PYGL (0.44) | F7F3HPGDKDM4EHSD17B10 | |
| SCHEMBL1201734 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1PYGLCHEK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4161902-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |
| EP-4149945-A1 | SUBSTITUTED TRICYCLIC AMIDES, ANALOGUES THEREOF, AND METHODS USING SAME | Arbutus Biopharma Corporation (CA) | 2023-03-22 | — | — | EP | disclosed |