Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397192 | 0.93 | ADORA3 (0.60) | ADORA3ALDH1A1KDM4EHPGDNPSR1 | |
| SCHEMBL28335019 | 0.93 | ADORA3 (0.63) | ADORA3ALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL30189329 | 0.93 | ADORA3 (0.63) | ADORA3ALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL395310 | 0.90 | ADORA3 (0.57) | ADORA3ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL30189327 | 0.90 | ADORA3 (0.57) | ADORA3ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL30189330 | 0.88 | ADORA3 (0.55) | ADORA3ALDH1A1KDM4EHPGDNPSR1 | |
| SCHEMBL30189523 | 0.88 | ALDH1A1 (0.57) | ADORA3ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL30189489 | 0.88 | ADORA3 (0.55) | ADORA3ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL30189331 | 0.87 | SMN1; SMN2 (0.55) | ADORA3ALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL397165 | 0.86 | ADORA3 (0.61) | ADORA3ALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115636782-B | Synthesis method of polyaryl substituted pyridine | 浙江工业大学 | 2024-07-19 | — | — | CN | disclosed |
| CN-115636782-A | Synthetic method of polyaryl substituted pyridine | 浙江工业大学 | 2023-01-24 | — | — | CN | disclosed |