⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14755756 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL16040200 | 0.98 | P2RX7 (0.50) | — | |
| SCHEMBL27599895 | 0.80 | — | — | |
| SCHEMBL16791674 | 0.78 | P2RX7 (0.49) | — | |
| SCHEMBL28562684 | 0.77 | — | — | |
| SCHEMBL220487 | 0.77 | — | — | |
| SCHEMBL27668397 | 0.77 | — | — | |
| SCHEMBL26081630 | 0.77 | — | — | |
| SCHEMBL29564726 | 0.77 | — | — | |
| SCHEMBL15500957 | 0.77 | P2RX7 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120035583-A | PAN-KRAS inhibitors | 米拉蒂治疗股份有限公司 | 2025-05-23 | — | — | CN | disclosed |
| US-11986471-B2 | Compounds and methods of use | TANGO THERAPEUTICS, INC. (US) | 2024-05-21 | — | — | US | disclosed |
| US-20230060499-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2023-03-02 | — | — | US | disclosed |
| US-11542256-B2 | Vinylheterocycles as Rho-associated coiled-coil kinase (ROCK) inhibitors | ANGION BIOMEDICA CORP. (US) | 2023-01-03 | — | — | US | disclosed |