Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783237 | 1.00 | ILK (0.54) | ILKKMT2AKDM4EATMGAA | |
| SCHEMBL543966 | 0.84 | ILK (0.57) | ILKKMT2AKDM4EATMGAA | |
| SCHEMBL1553043 | 0.84 | TSHR (0.51) | ILKGAAALDH1A1TSHRHSD17B10 | |
| SCHEMBL984327 | 0.83 | ILK (0.59) | ILKKMT2AKDM4EATMGAA | |
| SCHEMBL117199 | 0.83 | ILK (0.53) | ILKKMT2AKDM4EATMGAA | |
| SCHEMBL21685755 | 0.81 | ILK (0.51) | ILKKMT2AKDM4EATMGAA | |
| SCHEMBL5118299 | 0.80 | ALDH1A1 (0.47) | KMT2AKDM4EGAAALDH1A1LMNA | |
| SCHEMBL29226750 | 0.80 | ILK (0.59) | ILKKMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL19224594 | 0.74 | ALDH1A1 (0.59) | ILKKMT2AKDM4EATMGAA | |
| SCHEMBL20767897 | 0.74 | KDM4E (0.53) | ILKKMT2AKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |