Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.53 |
| ▸ | EPOR | P19235 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24038747 | 0.92 | LMNA (0.76) | HTTLMNASMN1; SMN2TGM2FOLH1 | |
| SCHEMBL9132655 | 0.90 | HTT (0.79) | HTTLMNASMN1; SMN2TGM2FOLH1 | |
| SCHEMBL20285821 | 0.89 | HTT (0.69) | HTTLMNASMN1; SMN2TGM2FOLH1 | |
| SCHEMBL5058688 | 0.89 | HTT (0.77) | HTTLMNASMN1; SMN2TGM2FOLH1 | |
| SCHEMBL18751657 | 0.89 | HTT (0.76) | HTTLMNASMN1; SMN2TGM2FOLH1 | |
| SCHEMBL17350181 | 0.88 | LMNA (0.67) | HTTLMNASMN1; SMN2TGM2FOLH1 | |
| SCHEMBL25330907 | 0.88 | LMNA (0.74) | HTTLMNASMN1; SMN2TGM2FOLH1 | |
| SCHEMBL7682044 | 0.88 | LMNA (0.69) | HTTLMNASMN1; SMN2TGM2FOLH1 | |
| SCHEMBL4857273 | 0.88 | HTT (0.88) | HTTLMNASMN1; SMN2TGM2FOLH1 | |
| SCHEMBL125577 | 0.88 | HTT (0.88) | HTTLMNASMN1; SMN2TGM2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4150009-A1 | FLUOROGENIC DIMER COMPOUND, USEFUL AS A PROBE FOR DETECTION OF ENDOGENOUS RECEPTORS | Université de Strasbourg (FR) | 2023-03-22 | — | — | EP | disclosed |