Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783365 | 1.00 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1OPRK1HTT | |
| SCHEMBL8085492 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1MAPTTP53 | |
| SCHEMBL20597519 | 0.81 | SMN1; SMN2 (0.46) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL2035753 | 0.81 | MEN1 (0.51) | ALDH1A1KMT2AMEN1MAPTTP53 | |
| SCHEMBL20714030 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL30189600 | 0.76 | ALDH1A1 (0.77) | ALDH1A1KMT2AMEN1MAPTTP53 | |
| SCHEMBL19782849 | 0.76 | ALDH1A1 (0.77) | ALDH1A1KMT2AMEN1MAPTTP53 | |
| SCHEMBL8086022 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1MAPTTP53 | |
| SCHEMBL10591137 | 0.73 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1MAPTTP53 | |
| SCHEMBL8040099 | 0.70 | SMN1; SMN2 (0.43) | ALDH1A1KMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |