Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783618 | 1.00 | MEN1 (0.39) | MEN1KMT2AAPPALDH1A1L3MBTL1 | |
| SCHEMBL19783632 | 0.88 | PNMT (0.41) | MEN1KMT2AALDH1A1L3MBTL1PNMT | |
| SCHEMBL30189741 | 0.88 | PNMT (0.41) | MEN1KMT2AALDH1A1L3MBTL1PNMT | |
| SCHEMBL21395444 | 0.79 | CYP3A4 (0.39) | MEN1KMT2AALDH1A1SCDLMNA | |
| SCHEMBL19783511 | 0.77 | KMT2A (0.38) | MEN1KMT2AALDH1A1POLB | |
| SCHEMBL19783775 | 0.76 | F2RL3 (0.55) | — | |
| SCHEMBL30187628 | 0.76 | F2RL3 (0.55) | — | |
| SCHEMBL19783627 | 0.76 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1L3MBTL1LMNA | |
| SCHEMBL30189938 | 0.76 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1L3MBTL1LMNA | |
| SCHEMBL19783475 | 0.74 | KMT2A (0.36) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |