SCHEMBL30189772

SCHEMBL30189772

CCOc1cnc2c(B3OC(C)(C)C(C)(C)O3)cc(C)cc2c1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
UCHL1 P09936 1/20 0.35
MAPT P10636 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19783710 1.00 UCHL1 (0.35) UCHL1MAPTCYP11B1CYP11B2
SCHEMBL29481814 0.88 UCHL1 (0.34) UCHL1CYP11B1CYP11B2
SCHEMBL19776254 0.88 UCHL1 (0.34) UCHL1CYP11B1CYP11B2
SCHEMBL19776260 0.86 UCHL1 (0.36) UCHL1
SCHEMBL29481764 0.86 UCHL1 (0.36) UCHL1
SCHEMBL30189781 0.82 F2RL3 (0.34)
SCHEMBL19783752 0.82 F2RL3 (0.34)
SCHEMBL19783709 0.80 F2RL3 (0.34) UCHL1
SCHEMBL30189815 0.76 SNCA (0.36) UCHL1
SCHEMBL19782697 0.76 SNCA (0.36) UCHL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN disclosed