Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2144122 | 1.00 | DUT (0.36) | DUTCA12CA1CA2CA9 | |
| SCHEMBL307184 | 0.83 | DUT (0.35) | DUTCA12CA1CA2CA9 | |
| SCHEMBL16065100 | 0.81 | DUT (0.39) | DUTCA12CA1CA2CA9 | |
| SCHEMBL31403630 | 0.80 | NUDT1 (0.58) | DUTCA12CA1CA2CA9 | |
| SCHEMBL19782447 | 0.80 | KCNH2 (0.33) | DUTCA12CA1CA2CA9 | |
| SCHEMBL17406997 | 0.80 | DUT (0.39) | DUTCA12CA1CA2CA9 | |
| SCHEMBL31157847 | 0.78 | ALOX5AP (0.36) | DUTCA12CA1CA2CA9 | |
| SCHEMBL26647056 | 0.78 | ALOX5AP (0.36) | DUTCA12CA1CA2CA9 | |
| SCHEMBL16973141 | 0.78 | KDM4E (0.44) | DUTCA12CA1CA2CA9 | |
| SCHEMBL29481761 | 0.78 | KDM4E (0.44) | DUTCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |