Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783030 | 1.00 | HSD17B10 (0.46) | HSD17B10HTTCYP3A4TDP1ALDH1A1 | |
| SCHEMBL19782397 | 0.82 | RECQL (0.39) | HSD17B10ALDH1A1POLBSMN1; SMN2TP53 | |
| SCHEMBL30189475 | 0.81 | RECQL (0.38) | ALDH1A1POLBSMN1; SMN2TSHRRECQL | |
| SCHEMBL19783074 | 0.81 | RECQL (0.38) | ALDH1A1POLBSMN1; SMN2TSHRRECQL | |
| SCHEMBL5309925 | 0.78 | HSD17B10 (0.52) | HSD17B10HTTCYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL30189925 | 0.75 | ALDH1A1 (0.45) | HSD17B10ALDH1A1POLBSMN1; SMN2KDM4E | |
| SCHEMBL19782957 | 0.75 | ALDH1A1 (0.45) | HSD17B10ALDH1A1POLBSMN1; SMN2KDM4E | |
| SCHEMBL19782827 | 0.75 | HTT (0.53) | HSD17B10HTTCYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL19782603 | 0.75 | HSD17B10 (0.49) | HSD17B10HTTCYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL30189823 | 0.75 | HSD17B10 (0.49) | HSD17B10HTTCYP3A4ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |