Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.50 |
| ▸ | PI4KA | P42356 | 5/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.50 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184747 | 1.00 | PIK3CD (0.50) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL23720038 | 0.81 | CYP3A4 (0.43) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL30526543 | 0.81 | PIK3CD (0.55) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL184566 | 0.81 | PIK3CD (0.55) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL184788 | 0.81 | PIK3CD (0.53) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL30526584 | 0.80 | PIK3CA (0.57) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL10049899 | 0.79 | PDE10A (0.44) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL30189846 | 0.79 | PDE10A (0.36) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL794336 | 0.79 | PDE10A (0.36) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB | |
| SCHEMBL1851332 | 0.78 | PDE10A (0.35) | PIK3CDPIK3CAPIK3CBPI4KAPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4531838-A1 | IMIDAZOPYRIDINE AND OXAZOLOPYRIDINE DERIVATIVES AND ANALOGS THEREOF, METHODS OF PREPARATION THEREOF, METHODS OF HIF-1/2A PATHWAY INHIBITION, AND INDUCTION OF FERROPTOSIS | Kuda Therapeutics, Inc. (US) | 2025-04-09 | — | — | EP | disclosed |
| EP-4463456-A1 | THIAZOLOPYRIDYL AMIDE DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | BeiGene, Ltd. (KY) | 2024-11-20 | — | — | EP | disclosed |
| WO-2024230578-A1 | CYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF | DANATLAS PHARMACEUTICALS CO., LTD. (CN) | 2024-11-14 | — | — | WO | disclosed |
| CN-118510778-A | Thiazolopyridylamide derivatives as inhibitors of DNA polymerase θ | 百济神州有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-117343025-A | Polymerizable liquid crystal compound, polymerizable composition, retardation film, transfer laminate, and optical member | 大日本印刷株式会社 | 2024-01-05 | — | — | CN | disclosed |
| WO-2023234970-A1 | IMIDAZOPYRIDINE AND OXAZOLOPYRIDINE DERIVATIVES AND ANALOGS THEREOF, METHODS OF PREPARATION THEREOF, METHODS OF HIF-1/2A PATHWAY INHIBITION, AND INDUCTION OF FERROPTOSIS | KUDA Therapeutics, Inc. (US) | 2023-12-07 | — | — | WO | disclosed |
| CN-111201220-B | Polymerizable liquid crystal compound, polymerizable composition, retardation film, transfer laminate, and optical member | 大日本印刷株式会社 | 2023-10-17 | — | — | CN | disclosed |
| WO-2023134708-A1 | THIAZOLOPYRIDYL AMIDE DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | BEIGENE , LTD. (KY) | 2023-07-20 | — | — | WO | disclosed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |