SCHEMBL23720038

SCHEMBL23720038

COc1ccccc1Oc1ccc2nc(N)sc2n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
POLB P06746 1/20 0.41
ALDH1A1 P00352 5/20 0.41
KDM4E B2RXH2 2/20 0.40
MAPK1 P28482 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
NPC1 O15118 2/20 0.40
MAPT P10636 2/20 0.40
RAB9A P51151 2/20 0.40
GAA P10253 1/20 0.40
THRB P10828 1/20 0.40
BLM P54132 1/20 0.40
ATM Q13315 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
MAP4K4 O95819 3/20 0.39
PIK3CD O00329 1/20 0.39
PIP5K1C O60331 1/20 0.39
PIK3CA P42336 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23720084 0.83 MAP4K4 (0.54) ALDH1A1NPC1MAPTRAB9AMAP4K4
SCHEMBL25500877 0.82 NPC1 (0.38) CYP3A4ALDH1A1L3MBTL1NPC1MAPT
SCHEMBL184747 0.81 PIK3CD (0.50) CYP3A4TDP1ALDH1A1L3MBTL1NPC1
SCHEMBL30189832 0.81 PIK3CD (0.50) CYP3A4TDP1ALDH1A1L3MBTL1NPC1
SCHEMBL21186282 0.79 NPC1 (0.55) CYP3A4TDP1ALDH1A1KDM4EL3MBTL1
SCHEMBL2849366 0.78 MAPT (0.46) CYP3A4POLBKDM4EL3MBTL1NPC1
SCHEMBL25909689 0.77 ABL1 (0.55) CYP3A4TDP1ALDH1A1KDM4ENPC1
SCHEMBL23720082 0.77 MAP4K4 (0.41) KDM4ENPC1MAPTRAB9AMAP4K4
SCHEMBL21186292 0.74 MEN1 (0.50) CYP3A4ALDH1A1KDM4EMAPK1L3MBTL1
SCHEMBL21186212 0.73 CYP3A4 (0.68) CYP3A4TDP1ALDH1A1MAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4097111-B9 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2025-10-29 EP disclosed
US-12415815-B2 Pyrido[2,3-e]oxazine derivatives as agricultural chemicals GLOBACHEM NV (BE) 2025-09-16 US disclosed
EP-4097111-B1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2025-07-23 EP disclosed
US-20230151023-A1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2023-05-18 US disclosed
US-20230151023-A1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2023-05-18 US disclosed
US-20230151023-A1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2023-05-18 US disclosed
WO-2021151919-A1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2021-08-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230151023-A1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS PNPO, HPD, PDXK CYP3A4 434/4885TDP1 2588/4885POLB 3680/4885
US-12415815-B2 Pyrido[2,3-e]oxazine derivatives as agricultural chemicals PNPO, HPD, PDXK CYP3A4 434/4885TDP1 2588/4885POLB 3680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.