Salicylaldehyde Benzoyl Hydrazone

Salicylaldehyde Benzoyl Hydrazone

SCHEMBL30193248

O=C(NN=Cc1ccccc1O)c1ccccc1

nearest known ligand 0.82

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.82
MAOA P21397 1/20 0.82
MAOB P27338 1/20 0.82
HTT P42858 3/20 0.78
NPC1 O15118 3/20 0.78
RAB9A P51151 2/20 0.78
L3MBTL1 Q9Y468 1/20 0.78
KMT2A Q03164 5/20 0.74
CA12 O43570 1/20 0.72
CA1 P00915 1/20 0.72
CA2 P00918 1/20 0.72
CA9 Q16790 1/20 0.72
KDM4E B2RXH2 3/20 0.71
MEN1 O00255 3/20 0.71
TDP1 Q9NUW8 2/20 0.71
TP53 P04637 1/20 0.71
CYP3A4 P08684 1/20 0.71
CYP2D6 P10635 1/20 0.71
HPGD P15428 1/20 0.71
MAPK1 P28482 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicylaldehyde Benzoyl Hydrazone SCHEMBL414978 1.00 KDM1A (0.82) KDM1AMAOAMAOBHTTNPC1
Salicylaldehyde Benzoyl Hydrazone SCHEMBL414977 1.00 KDM1A (0.82) KDM1AMAOAMAOBHTTNPC1
Salicylaldehyde Benzoyl Hydrazone SCHEMBL6638532 1.00 KDM1A (0.82) KDM1AMAOAMAOBHTTNPC1
SCHEMBL684534 0.91 KDM1A (0.78) KDM1AMAOAMAOBHTTNPC1
SCHEMBL15176803 0.90 KDM1A (1.00) KDM1AMAOAMAOBHTTNPC1
SCHEMBL19283316 0.90 KDM1A (1.00) KDM1AMAOAMAOBHTTNPC1
SCHEMBL14712666 0.90 KDM1A (1.00) KDM1AMAOAMAOBHTTNPC1
SCHEMBL14983946 0.89 NOX4 (0.69) KDM1AMAOAMAOBHTTNPC1
SCHEMBL6749929 0.89 NOX4 (0.69) KDM1AMAOAMAOBHTTNPC1
SCHEMBL12746361 0.89 KDM1A (0.81) KDM1AMAOAMAOBHTTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111848441-B N-substituted benzoyl hydrazone compound and preparation method and application thereof 山东中新科农生物科技有限公司 2023-02-17 CN disclosed