Salicylaldehyde Benzoyl Hydrazone

Salicylaldehyde Benzoyl Hydrazone

SCHEMBL414977

O=C(N/N=C/c1ccccc1O)c1ccccc1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.82
MAOA P21397 1/20 0.82
MAOB P27338 1/20 0.82
HTT P42858 3/20 0.78
NPC1 O15118 3/20 0.78
RAB9A P51151 2/20 0.78
L3MBTL1 Q9Y468 1/20 0.78
KMT2A Q03164 5/20 0.74
CA12 O43570 1/20 0.72
CA1 P00915 1/20 0.72
CA2 P00918 1/20 0.72
CA9 Q16790 1/20 0.72
KDM4E B2RXH2 3/20 0.71
MEN1 O00255 3/20 0.71
TDP1 Q9NUW8 2/20 0.71
TP53 P04637 1/20 0.71
CYP3A4 P08684 1/20 0.71
CYP2D6 P10635 1/20 0.71
HPGD P15428 1/20 0.71
MAPK1 P28482 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Salicylaldehyde Benzoyl Hydrazone SCHEMBL414978 1.00 KDM1A (0.82) KDM1AMAOAMAOBHTTNPC1
Salicylaldehyde Benzoyl Hydrazone SCHEMBL30193248 1.00 KDM1A (0.82) KDM1AMAOAMAOBHTTNPC1
Salicylaldehyde Benzoyl Hydrazone SCHEMBL6638532 1.00 KDM1A (0.82) KDM1AMAOAMAOBHTTNPC1
SCHEMBL684534 0.91 KDM1A (0.78) KDM1AMAOAMAOBHTTNPC1
SCHEMBL15176803 0.90 KDM1A (1.00) KDM1AMAOAMAOBHTTNPC1
SCHEMBL19283316 0.90 KDM1A (1.00) KDM1AMAOAMAOBHTTNPC1
SCHEMBL14712666 0.90 KDM1A (1.00) KDM1AMAOAMAOBHTTNPC1
SCHEMBL14983946 0.89 NOX4 (0.69) KDM1AMAOAMAOBHTTNPC1
SCHEMBL6749929 0.89 NOX4 (0.69) KDM1AMAOAMAOBHTTNPC1
SCHEMBL12746361 0.89 KDM1A (0.81) KDM1AMAOAMAOBHTTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707910-A Multi-stimulus response Zn (II) -DASA complex molecular switch and preparation method and application thereof 南京理工大学 2025-03-28 CN claimed
CN-119707910-A Multi-stimulus response Zn (II) -DASA complex molecular switch and preparation method and application thereof 南京理工大学 2025-03-28 CN disclosed
WO-2023183559-A1 ENGINEERED IONOPHORES FOR TRANSPORT OF METAL IONS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2023-09-28 WO disclosed
US-20210238140-A1 Compounds for Targeting Cancer Stem Cells THE GENERAL HOSPITAL CORPORATION 2021-08-05 US disclosed
US-20180072675-A1 ANTIMICROBIAL PYRIDINOHYDRAZIDE AND HYDRAZOMETHYLPYRIDINE-BASED AGENTS BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE 2018-03-15 US disclosed
WO-2017219086-A1 ANTI-AGEING COMPOUNDS THE UNIVERSITY OF SYDNEY (AU) 2017-12-28 WO disclosed
US-8906829-B2 Synergistic algicidal compositions including hydrazone derivatives and copper DOW AGROSCIENCES LLC (US) 2014-12-09 US disclosed
US-8715745-B2 Fungicidal compositions including hydrazone derivatives and copper DOW AGROSCIENCES, LLC. (US) 2014-05-06 US disclosed
US-8563472-B2 Synergistic fungicidal and algicidal compositions including 2-hydroxyphenylaldehyde and 2-hydroxyphenylketone heterocycloyhydrazones and copper DOW AGROSCIENCES, LLC. (US) 2013-10-22 US disclosed
US-8476194-B2 Fungicidal compositions including hydrazone derivatives and copper DOW AGROSCIENCES, LLC (US) 2013-07-02 US disclosed
US-20040104377-A1 Non-toxic corrosion-protection pigments based on rare earth elements UNIVERSITY OF DAYTON 2004-06-03 US disclosed
WO-2004022775-A1 METHOD AND PROBE FOR IDENTIFYING BACTERIAL VIRULENCE MODIFYING AGENTS, AGENTS THUS IDENTIFIED, AND THEIR USE INNATE PHARMACEUTICALS AB (SE) 2004-03-18 WO disclosed
US-20040020568-A1 Non-toxic corrosion-protection conversion coats based on rare earth elements DAYTON, UNIVERSITY OF 2004-02-05 US disclosed
US-20040016910-A1 Non-toxic corrosion-protection rinses and seals based on rare earth elements DAYTON, UNIVERSITY OF 2004-01-29 US disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 US disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 US disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210238140-A1 Compounds for Targeting Cancer Stem Cells G3BP1, G3BP2, HMGB2 KDM1A 2810/4885MAOA 4879/4885MAOB 4771/4885
US-20180072675-A1 ANTIMICROBIAL PYRIDINOHYDRAZIDE AND HYDRAZOMETHYLPYRIDINE-BASED AGENTS CLPP, HPD, PDXK KDM1A 1666/4885MAOA 1864/4885MAOB 1649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.