Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.75 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.75 |
| ▸ | JUN | P05412 | 4/20 | 0.70 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tylophorine SCHEMBL31497488 | 1.00 | HIF1A (0.75) | HIF1AEPAS1JUNEHMT2DRD1 | |
| (S)-Tylophorine SCHEMBL523625 | 1.00 | HIF1A (0.75) | HIF1AEPAS1JUNEHMT2DRD1 | |
| (+/-)-Tylophorine SCHEMBL523626 | 1.00 | HIF1A (0.75) | HIF1AEPAS1JUNEHMT2DRD1 | |
| Tylophorine SCHEMBL8977400 | 1.00 | HIF1A (0.75) | HIF1AEPAS1JUNEHMT2DRD1 | |
| (S)-Tylophorine SCHEMBL30116767 | 1.00 | HIF1A (0.75) | HIF1AEPAS1JUNEHMT2DRD1 | |
| (S)-Tylophorine SCHEMBL5610438 | 0.99 | HIF1A (0.73) | HIF1AEPAS1JUNEHMT2 | |
| SCHEMBL13222745 | 0.96 | HIF1A (0.81) | HIF1AEPAS1JUNEHMT2 | |
| SCHEMBL30637462 | 0.96 | HIF1A (0.81) | HIF1AEPAS1JUNEHMT2 | |
| SCHEMBL13222766 | 0.94 | HIF1A (0.80) | HIF1AEPAS1JUNEHMT2 | |
| SCHEMBL13222824 | 0.93 | JUN (0.81) | HIF1AEPAS1JUNDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115702908-A | Probiotic composition for the treatment and prevention of colorectal cancer | 香港中文大学 | 2023-02-17 | — | — | CN | disclosed |