Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 1.00 |
| ▸ | PAX8 | Q06710 | 1/20 | 1.00 |
| ▸ | PRKCA | P17252 | 10/20 | 0.84 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.80 |
| ▸ | PRKCG | P05129 | 1/20 | 0.80 |
| ▸ | PRKCB | P05771 | 1/20 | 0.80 |
| ▸ | PRKCH | P24723 | 1/20 | 0.80 |
| ▸ | PRKCI | P41743 | 1/20 | 0.80 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.80 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.80 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.80 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.80 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.80 |
| ▸ | TOP1 | P11387 | 12/20 | 0.62 |
| ▸ | EGFR | P00533 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rebeccamycin SCHEMBL14069957 | 1.00 | DYRK1A (1.00) | DYRK1APAX8PRKCAPRKD3PRKCG | |
| Rebeccamycin SCHEMBL24695 | 1.00 | DYRK1A (1.00) | DYRK1APAX8PRKCAPRKD3PRKCG | |
| Rebeccamycin SCHEMBL12961242 | 1.00 | DYRK1A (1.00) | DYRK1APAX8PRKCAPRKD3PRKCG | |
| Rebeccamycin SCHEMBL32690193 | 1.00 | DYRK1A (1.00) | DYRK1APAX8PRKCAPRKD3PRKCG | |
| SCHEMBL10027492 | 0.89 | DYRK1A (0.81) | DYRK1APAX8PRKCAPRKD3PRKCG | |
| SCHEMBL7165791 | 0.86 | DYRK1A (0.76) | DYRK1APAX8PRKCAPRKD3PRKCG | |
| Rebeccamycin SCHEMBL19100060 | 0.86 | DYRK1A (0.75) | DYRK1APAX8PRKCAPRKD3PRKCG | |
| Becatecarin SCHEMBL5953888 | 0.85 | PRKCA (0.78) | DYRK1APAX8PRKCAPRKD3PRKCG | |
| Becatecarin SCHEMBL5953787 | 0.85 | PRKCA (0.78) | DYRK1APAX8PRKCAPRKD3PRKCG | |
| Becatecarin SCHEMBL31237559 | 0.85 | PRKCA (0.78) | DYRK1APAX8PRKCAPRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024241248-A1 | COMPOUNDS TARGETING KRAS G12D MUTATIONS AND THEIR USES | INNOPHARMASCREEN INC. (KR) | 2024-11-28 | — | — | WO | disclosed |
| EP-4392449-A1 | ANTIGEN-BINDING POLYPEPTIDES AGAINST CD73 | Universitätsklinikum Hamburg-Eppendorf (DE) | 2024-07-03 | — | — | EP | disclosed |
| EP-4388003-A1 | ANTIGEN-BINDING POLYPEPTIDES AGAINST CD39 | Universitätsklinikum Hamburg-Eppendorf (DE) | 2024-06-26 | — | — | EP | disclosed |
| WO-2023021185-A1 | ANTIGEN-BINDING POLYPEPTIDES AGAINST CD39 | Universitätsklinikum Hamburg-Eppendorf (DE) | 2023-02-23 | — | — | WO | disclosed |
| WO-2023021186-A1 | ANTIGEN-BINDING POLYPEPTIDES AGAINST CD73 | Universitätsklinikum Hamburg-Eppendorf (DE) | 2023-02-23 | — | — | WO | disclosed |