SCHEMBL30194960

SCHEMBL30194960

O=C1CCC(N2Cc3cc(C#Cc4cccnn4)ccc3C2=O)C(=O)N1

nearest known ligand 0.60

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ IKZF2 Q9UKS7 11/20 0.60
▸ CRBN Q96SW2 9/20 0.56
▸ CSNK1A1 P48729 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23250036 0.82 CRBN (0.62) IKZF2CRBNCSNK1A1
SCHEMBL29873934 0.82 CRBN (0.62) IKZF2CRBNCSNK1A1
SCHEMBL30569130 0.81 CRBN (0.69) IKZF2CRBNCSNK1A1
SCHEMBL24637376 0.81 CRBN (0.69) IKZF2CRBNCSNK1A1
SCHEMBL25210909 0.81 IKZF2 (0.61) IKZF2CRBNCSNK1A1
SCHEMBL30416805 0.81 IKZF2 (0.61) IKZF2CRBNCSNK1A1
SCHEMBL23267271 0.79 CRBN (0.64) IKZF2CRBNCSNK1A1
SCHEMBL21877059 0.79 CRBN (0.64) IKZF2CRBNCSNK1A1
SCHEMBL21760044 0.78 CRBN (0.69) IKZF2CRBNCSNK1A1
SCHEMBL24601235 0.78 CRBN (0.69) IKZF2CRBNCSNK1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240383908-A1 SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER HINOVA PHARMACEUTICALS INC. (CN) 2024-11-21 — — US disclosed
EP-4368614-A1 SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER Hinova Pharmaceuticals Inc. (CN) 2024-05-15 — — EP disclosed
WO-2023280237-A1 SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER 海创药业股份有限公司 2023-01-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240383908-A1 SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER DUSP1, PPM1D, PTPN1 IKZF2 1349/4885CRBN 576/4885CSNK1A1 222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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