Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 2/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30970215 | 0.91 | CYP2D6 (0.46) | AGTR2CYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL30195155 | 0.91 | PIK3CA (0.40) | AGTR2EDNRAEDNRB | |
| SCHEMBL30194921 | 0.89 | AGTR2 (0.39) | AGTR2EDNRAEDNRBALOX5APFEN1 | |
| SCHEMBL30195009 | 0.89 | AGTR2 (0.47) | AGTR2 | |
| SCHEMBL30195138 | 0.89 | AGTR2 (0.47) | AGTR2GRM2EDNRAEDNRB | |
| SCHEMBL30195166 | 0.87 | AGTR2 (0.43) | AGTR2EDNRAEDNRB | |
| SCHEMBL29958715 | 0.86 | AGTR2 (0.54) | AGTR2GRM2 | |
| SCHEMBL30672031 | 0.86 | AGTR2 (0.54) | AGTR2GRM2 | |
| SCHEMBL30672029 | 0.84 | AGTR2 (0.51) | AGTR2 | |
| SCHEMBL29958687 | 0.84 | AGTR2 (0.51) | AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367110-A1 | NEW SELECTIVE ANGIOTENSIN II COMPOUNDS | Vicore Pharma AB (SE) | 2024-05-15 | — | — | EP | claimed |
| CN-117916229-A | Novel selective angiotensin II compounds | 维科尔药物公司 | 2024-04-19 | — | — | CN | claimed |
| WO-2023281271-A1 | NEW SELECTIVE ANGIOTENSIN II COMPOUNDS | VICORE PHARMA AB (SE) | 2023-01-12 | — | — | WO | claimed |
| CN-117916229-A | Novel selective angiotensin II compounds | 维科尔药物公司 | 2024-04-19 | — | — | CN | disclosed |
| WO-2023281271-A1 | NEW SELECTIVE ANGIOTENSIN II COMPOUNDS | VICORE PHARMA AB (SE) | 2023-01-12 | — | — | WO | disclosed |