SCHEMBL29958715

SCHEMBL29958715

COC(=O)NS(=O)(=O)c1ccc(CC(C)C)cc1-c1ccc(Cn2ccnc2C(C)C)c(F)c1

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 18/20 0.54
AGTR1 P30556 3/20 0.40
CYP3A4 P08684 1/20 0.40
GRM2 Q14416 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30672031 1.00 AGTR2 (0.54) AGTR2AGTR1CYP3A4GRM2
SCHEMBL30672029 0.93 AGTR2 (0.51) AGTR2AGTR1
SCHEMBL29958687 0.93 AGTR2 (0.51) AGTR2AGTR1
SCHEMBL29958604 0.91 AGTR2 (0.48) AGTR2AGTR1CYP3A4
SCHEMBL29958531 0.90 AGTR2 (0.62) AGTR2AGTR1
SCHEMBL29958672 0.90 AGTR2 (0.49) AGTR2AGTR1
SCHEMBL29958721 0.90 AGTR2 (0.56) AGTR2AGTR1CYP3A4
SCHEMBL25576366 0.90 AGTR2 (0.56) AGTR2AGTR1CYP3A4
SCHEMBL30195042 0.86 AGTR2 (0.40) AGTR2GRM2
SCHEMBL30672030 0.85 AGTR2 (0.52) AGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240182461-A1 SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS VICORE PHARMA AB (SE) 2024-06-06 US claimed
EP-4313953-A1 SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS Vicore Pharma AB (SE) 2024-02-07 EP claimed
WO-2022200785-A1 SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS VICORE PHARMA AB (SE) 2022-09-29 WO claimed
US-20240182461-A1 SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS VICORE PHARMA AB (SE) 2024-06-06 US disclosed
EP-4313953-A1 SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS Vicore Pharma AB (SE) 2024-02-07 EP disclosed
WO-2022200785-A1 SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS VICORE PHARMA AB (SE) 2022-09-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240182461-A1 SELECTIVE ANGIOTENSIN II RECEPTOR LIGANDS AGTR1, AGTR2, MSR1 AGTR2 2/4885AGTR1 1/4885CYP3A4 615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.