SCHEMBL30195092

SCHEMBL30195092

CC(C)Cc1ccc(S(=O)(=O)Nc2ncc(C#N)cn2)c(-c2ccc(Cn3ccnc3C(C)(C)C)c(F)c2)c1

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 16/20 0.49
PIK3C3 Q8NEB9 1/20 0.36
CYP3A4 P08684 1/20 0.34
BTK Q06187 1/20 0.33
ALOX5AP P20292 1/20 0.33
FEN1 P39748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30195170 0.92 AGTR2 (0.48) AGTR2CYP3A4
SCHEMBL30195090 0.91 AGTR2 (0.43) AGTR2CYP3A4
SCHEMBL30195053 0.90 AGTR2 (0.49) AGTR2CYP3A4
SCHEMBL30195087 0.90 AGTR2 (0.47) AGTR2CYP3A4
SCHEMBL30195009 0.90 AGTR2 (0.47) AGTR2CYP3A4
SCHEMBL30195027 0.90 AGTR2 (0.49) AGTR2
SCHEMBL30195011 0.90 AGTR2 (0.51) AGTR2CYP3A4ALOX5APFEN1
SCHEMBL30195048 0.89 AGTR2 (0.42) AGTR2CYP3A4
SCHEMBL30195142 0.84 AGTR2 (0.42) AGTR2CYP3A4
SCHEMBL23831132 0.84 AGTR2 (0.47) AGTR2CYP3A4BTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4367110-A1 NEW SELECTIVE ANGIOTENSIN II COMPOUNDS Vicore Pharma AB (SE) 2024-05-15 EP claimed
CN-117916229-A Novel selective angiotensin II compounds 维科尔药物公司 2024-04-19 CN claimed
WO-2023281271-A1 NEW SELECTIVE ANGIOTENSIN II COMPOUNDS VICORE PHARMA AB (SE) 2023-01-12 WO claimed
CN-117916229-A Novel selective angiotensin II compounds 维科尔药物公司 2024-04-19 CN disclosed
WO-2023281271-A1 NEW SELECTIVE ANGIOTENSIN II COMPOUNDS VICORE PHARMA AB (SE) 2023-01-12 WO disclosed