Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 14/20 | 0.42 |
| ▸ | EDNRA | P25101 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30195075 | 0.91 | PIK3CA (0.41) | AGTR2EDNRAABCB11CYP3A4PIK3CA | |
| SCHEMBL30195006 | 0.90 | AGTR2 (0.49) | AGTR2EDNRAABCB11CYP3A4PIK3CA | |
| SCHEMBL30195048 | 0.88 | AGTR2 (0.42) | AGTR2EDNRAABCB11CYP3A4PIK3CA | |
| SCHEMBL30195009 | 0.88 | AGTR2 (0.47) | AGTR2CYP3A4 | |
| SCHEMBL30195030 | 0.87 | AGTR2 (0.42) | AGTR2EDNRACYP3A4 | |
| SCHEMBL30195170 | 0.86 | AGTR2 (0.48) | AGTR2CYP3A4 | |
| SCHEMBL30195091 | 0.86 | ALOX5AP (0.47) | AGTR2EDNRACYP3A4 | |
| SCHEMBL30195090 | 0.85 | AGTR2 (0.43) | AGTR2CYP3A4 | |
| SCHEMBL29958721 | 0.85 | AGTR2 (0.56) | AGTR2CYP3A4 | |
| SCHEMBL25576366 | 0.85 | AGTR2 (0.56) | AGTR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367110-A1 | NEW SELECTIVE ANGIOTENSIN II COMPOUNDS | Vicore Pharma AB (SE) | 2024-05-15 | — | — | EP | claimed |
| CN-117916229-A | Novel selective angiotensin II compounds | 维科尔药物公司 | 2024-04-19 | — | — | CN | claimed |
| WO-2023281271-A1 | NEW SELECTIVE ANGIOTENSIN II COMPOUNDS | VICORE PHARMA AB (SE) | 2023-01-12 | — | — | WO | claimed |
| CN-117916229-A | Novel selective angiotensin II compounds | 维科尔药物公司 | 2024-04-19 | — | — | CN | disclosed |
| WO-2023281271-A1 | NEW SELECTIVE ANGIOTENSIN II COMPOUNDS | VICORE PHARMA AB (SE) | 2023-01-12 | — | — | WO | disclosed |