Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 4/20 | 0.45 |
| ▸ | PREP | P48147 | 3/20 | 0.45 |
| ▸ | DPP4 | P27487 | 8/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 9/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.43 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.43 |
| ▸ | GLMN | Q92990 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2849687 | 1.00 | FAP (0.45) | FAPPREPDPP4DPP9DPP8 | |
| SCHEMBL2849682 | 1.00 | FAP (0.45) | FAPPREPDPP4DPP9DPP8 | |
| SCHEMBL3526857 | 0.92 | FAP (0.42) | FAPPREPDPP4DPP9DPP8 | |
| SCHEMBL3526856 | 0.92 | FAP (0.42) | FAPPREPDPP4DPP9DPP8 | |
| SCHEMBL301874 | 0.80 | FAP (0.47) | FAPPREPDPP4DPP9DPP8 | |
| SCHEMBL2842224 | 0.79 | FAP (0.54) | FAPPREPDPP4DPP9DPP8 | |
| SCHEMBL5748938 | 0.78 | PREP (0.47) | FAPPREPDPP4DPP9DPP8 | |
| SCHEMBL2847963 | 0.78 | PREP (0.47) | FAPPREPDPP4DPP9DPP8 | |
| SCHEMBL2852307 | 0.78 | DPP4 (0.49) | FAPPREPDPP4DPP9DPP8 | |
| SCHEMBL2851493 | 0.78 | PREP (0.49) | FAPPREPDPP4DPP9DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4853965-B2 | — | — | 2012-01-11 | — | — | JP | claimed |
| JP-2007504120-A | — | — | 2007-03-01 | — | — | JP | claimed |
| EP-1664031-A2 | ADAMANTANE AND AZABICYCLO-OCTANE AND NONANE DERIVATIVES PROCESS OF THEIR PREPARATION AND THEIR USE AS DPP-IV INHIBITORS | Sanofi-Aventis (FR) | 2006-06-07 | — | — | EP | claimed |
| WO-2005021536-A2 | ADAMANTANE AND AZABICYCLO-OCTANE AND NONANE DERIVATIVES, PROCESS OF THEIR PREPARATION AND THEIR USE AS DPP-IV INHIBITORS | SANOFI-AVENTIS (FR) | 2005-03-10 | — | — | WO | claimed |