Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 9/20 | 0.42 |
| ▸ | PREP | P48147 | 8/20 | 0.42 |
| ▸ | DPP4 | P27487 | 8/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.39 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3526856 | 1.00 | FAP (0.42) | FAPPREPDPP4DPP9DPP8 | |
| SCHEMBL2849687 | 0.92 | FAP (0.45) | FAPPREPDPP4DPP9DPP8 | |
| SCHEMBL301976 | 0.92 | FAP (0.45) | FAPPREPDPP4DPP9DPP8 | |
| SCHEMBL2849682 | 0.92 | FAP (0.45) | FAPPREPDPP4DPP9DPP8 | |
| SCHEMBL301874 | 0.90 | FAP (0.47) | FAPPREPDPP4DPP9DPP8 | |
| SCHEMBL2842224 | 0.76 | FAP (0.54) | FAPPREPDPP4DPP9DPP8 | |
| SCHEMBL5748938 | 0.75 | PREP (0.47) | FAPPREPDPP4DPP9DPP8 | |
| SCHEMBL2847963 | 0.75 | PREP (0.47) | FAPPREPDPP4DPP9DPP8 | |
| SCHEMBL2847195 | 0.73 | DPP4 (0.52) | FAPPREPDPP4DPP9DPP8 | |
| Hydrochloric Acid SCHEMBL2841470 | 0.73 | DPP4 (0.51) | FAPPREPDPP4DPP9DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7652021-B2 | (2S)-4,4-difluoro-1-{N-[3-(pyrimidin-2-ylamino)-1-adamantyl]glycyl}pyrrolidine-2-carbonitrile; dipeptidyl peptidase IV enzyme inhibitors; non-insulin dependent diabetes mellitus | SANOFI-AVENTIS (FR) | 2010-01-26 | — | — | US | disclosed |
| US-20060276487-A1 | New compounds useful for DPP-IV enzyme inhibition | SANOFI-AVENTIS (FR) | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276487-A1 | New compounds useful for DPP-IV enzyme inhibition | DPP4, DPP7, DPP9 | FAP 22/4885PREP 29/4885DPP4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.