Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 2/20 | 0.59 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30083267 | 0.90 | ALDH1A1 (0.58) | GPR119MAPTALDH1A1LMNAPDK2 | |
| SCHEMBL62718 | 0.90 | ALDH1A1 (0.58) | GPR119MAPTALDH1A1LMNAPDK2 | |
| SCHEMBL2333786 | 0.90 | GPR119 (0.58) | PARP14GPR119MAPTALDH1A1LMNA | |
| SCHEMBL13033394 | 0.87 | GPR119 (0.56) | PARP14GPR119MAPTALDH1A1LMNA | |
| SCHEMBL31017510 | 0.87 | GPR119 (0.56) | PARP14GPR119MAPTALDH1A1LMNA | |
| SCHEMBL265132 | 0.86 | GPR119 (0.60) | GPR119MAPTALDH1A1LMNAPDK2 | |
| SCHEMBL30198151 | 0.86 | GPR119 (0.60) | GPR119MAPTALDH1A1LMNAPDK2 | |
| SCHEMBL23228892 | 0.86 | GPR119 (0.55) | PARP14GPR119MAPTALDH1A1LMNA | |
| SCHEMBL6413155 | 0.86 | GPR119 (0.55) | PARP14GPR119MAPTALDH1A1LMNA | |
| SCHEMBL22396684 | 0.85 | GPR119 (0.54) | PARP14GPR119MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262297-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | DARK BLUE THERAPEUTICS LTD (GB) | 2025-12-26 | — | — | WO | disclosed |
| US-20050014765-A1 | Aryl-heteroaromatic products, compositions comprising them and use | AVENTIS PHARMA S.A. (FR) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014765-A1 | Aryl-heteroaromatic products, compositions comprising them and use | AHR, ARNT, MYC | PARP14 951/4885GPR119 3382/4885MAPT 3583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.