SCHEMBL301986

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL303299	0.93	NAMPT (0.48)	NAMPTCYP11B1HTTLMNANPSR1
	SCHEMBL18487092	0.92	NAMPT (0.54)	NAMPTMAPTHTTLMNAGAA
	SCHEMBL3377911	0.91	MAPT (0.54)	MAPTHTTGAAMCL1NR1I2
	SCHEMBL3380874	0.86	NR3C1 (0.54)	MAPTHTTGAAKEAP1NFE2L2
	SCHEMBL18487075	0.84	NAMPT (0.42)	NAMPTCYP11B1HTTLMNANPSR1
	SCHEMBL303030	0.84	GRM2 (0.54)	CYP11B1MAPTHTTLMNANPSR1
	SCHEMBL3380436	0.82	NR1H2 (0.45)	MAPTLMNAALDH1A1MCL1
	SCHEMBL302950	0.82	NR3C1 (0.55)	MAPTHTTLMNAGAAKEAP1
	SCHEMBL303293	0.82	GAA (0.63)	MAPTHTTLMNAGAA
	SCHEMBL18487096	0.81	MEN1 (0.46)	MAPTALDH1A1MCL1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.