SCHEMBL302950

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3380436	0.91	NR1H2 (0.45)	NR3C1PGRMAPTMCL1LMNA
	SCHEMBL3377911	0.91	MAPT (0.54)	NR3C1MAPTMCL1BCL2L1GAA
	SCHEMBL3380874	0.90	NR3C1 (0.54)	NR3C1MAPTMCL1BCL2L1GAA
	SCHEMBL3378995	0.85	LMNA (0.51)	NR3C1PGRMAPTPOLBMCL1
	SCHEMBL303293	0.85	GAA (0.63)	NR3C1MAPTLMNAGAAHTT
	SCHEMBL301832	0.85	LMNA (0.44)	NR3C1PGRMAPTMCL1LMNA
	SCHEMBL301986	0.82	NAMPT (0.51)	MAPTMCL1LMNAGAAHTT
	SCHEMBL303366	0.81	L3MBTL1 (0.56)	MAPTPOLBLMNAGAAHTT
	SCHEMBL304757	0.81	L3MBTL1 (0.50)	MAPTPOLBMCL1TAS2R14GAA
	SCHEMBL301844	0.79	KEAP1 (0.49)	MAPTPOLBMCL1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.