Arenarine C

Arenarine C

SCHEMBL30199121

COc1ccc2c(c1)[nH]c1c(C(C)=O)nccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 14/20 1.00
ACHE P22303 3/20 1.00
BCHE P06276 3/20 1.00
MAOA P21397 3/20 0.65
GSK3B P49841 2/20 0.65
CLK1 P49759 2/20 0.65
CDK5 Q00535 2/20 0.65
CDK5R1 Q15078 2/20 0.65
KDM4E B2RXH2 1/20 0.65
DYRK3 O43781 1/20 0.65
CCNT1 O60563 1/20 0.65
CCNB2 O95067 1/20 0.65
ALDH1A1 P00352 1/20 0.65
CYP1A2 P05177 1/20 0.65
CDK1 P06493 1/20 0.65
CYP3A4 P08684 1/20 0.65
ADRA2A P08913 1/20 0.65
CYP2D6 P10635 1/20 0.65
CCNB1 P14635 1/20 0.65
HPGD P15428 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arenarine C SCHEMBL645800 1.00 DYRK1A (1.00) DYRK1AACHEBCHEMAOAGSK3B
SCHEMBL25832010 0.90 DYRK1A (0.81) DYRK1AACHEBCHEMAOAGSK3B
SCHEMBL30601059 0.90 DYRK1A (0.81) DYRK1AACHEBCHEMAOAGSK3B
SCHEMBL25832011 0.88 DYRK1A (0.79) DYRK1AACHEBCHEMAOAGSK3B
SCHEMBL30199348 0.88 DYRK1A (0.79) DYRK1AACHEBCHEMAOAGSK3B
Harmic Acid Methyl Ester SCHEMBL25294090 0.88 DYRK1A (0.79) DYRK1AACHEBCHEMAOAGSK3B
Trigonostemine B SCHEMBL30492900 0.82 DYRK1A (0.69) DYRK1AACHEBCHEMAOAGSK3B
SCHEMBL2768479 0.81 DYRK1A (0.68) DYRK1AACHEBCHEMAOAGSK3B
SCHEMBL2768305 0.81 DYRK1A (0.68) DYRK1AACHEBCHEMAOAGSK3B
SCHEMBL16123485 0.79 DYRK1A (0.74) DYRK1AACHEBCHEMAOAGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2926119-B1 METHOD OF MARKING OF MATERIAL, MARKED MATERIAL AND METHOD FOR AUTHENTICATING A MATERIAL SICPA HOLDING SA (CH) 2023-02-22 EP claimed