Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 12/20 | 0.79 |
| ▸ | ACHE | P22303 | 2/20 | 0.79 |
| ▸ | BCHE | P06276 | 2/20 | 0.79 |
| ▸ | CLK1 | P49759 | 3/20 | 0.64 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.64 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.64 |
| ▸ | GSK3B | P49841 | 2/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.64 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.64 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CDK1 | P06493 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199348 | 1.00 | DYRK1A (0.79) | DYRK1AACHEBCHECLK1CDK5 | |
| Arenarine C SCHEMBL30199121 | 0.88 | DYRK1A (1.00) | DYRK1AACHEBCHECLK1CDK5 | |
| SCHEMBL25832010 | 0.88 | DYRK1A (0.81) | DYRK1AACHEBCHECLK1CDK5 | |
| SCHEMBL30601059 | 0.88 | DYRK1A (0.81) | DYRK1AACHEBCHECLK1CDK5 | |
| Arenarine C SCHEMBL645800 | 0.88 | DYRK1A (1.00) | DYRK1AACHEBCHECLK1CDK5 | |
| Harmic Acid Methyl Ester SCHEMBL25294090 | 0.87 | DYRK1A (0.79) | DYRK1AACHEBCHECLK1CDK5 | |
| Trigonostemine B SCHEMBL30492900 | 0.81 | DYRK1A (0.69) | DYRK1AACHEBCHECLK1CDK5 | |
| SCHEMBL23150327 | 0.80 | DYRK1A (0.72) | DYRK1AACHEBCHECLK1CDK5 | |
| SCHEMBL31546623 | 0.79 | DYRK1A (0.57) | DYRK1AACHEBCHECLK1CDK5 | |
| Harmine SCHEMBL9481427 | 0.78 | MAOA (1.00) | DYRK1AACHEBCHECLK1CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130076-A2 | TARGETS AND PATHWAYS FOR THE PRODUCTION OF ALKALOIDAL COMPOUNDS | Empyrean Neuroscience, Inc. (US) | 2023-07-06 | — | — | WO | disclosed |
| WO-2023130078-A2 | GENETICALLY MODIFIED MYCELIUM FOR PRODUCING PSYCHOTROPIC ALKALOIDS | Empyrean Neuroscience, Inc. (US) | 2023-07-06 | — | — | WO | disclosed |
| WO-2023130075-A2 | GENETICALLY MODIFIED ORGANISMS FOR PRODUCING PSYCHOTROPIC ALKALOIDS | Empyrean Neuroscience, Inc. (US) | 2023-07-06 | — | — | WO | disclosed |