SCHEMBL30199134

SCHEMBL30199134

CCS(=O)(=O)c1cccnc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 1/20 0.59
PSIP1 O75475 1/20 0.56
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
MAPT P10636 1/20 0.44
NAMPT P43490 2/20 0.43
KEAP1 Q14145 1/20 0.43
NFE2L2 Q16236 1/20 0.43
CHRNB2 P17787 1/20 0.42
CHRNA4 P43681 1/20 0.42
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.41
PTGS2 P35354 1/20 0.41
GAA P10253 1/20 0.41
GLO1 Q04760 1/20 0.41
SLC40A1 Q9NP59 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10622054 1.00 NAPRT (0.59) NAPRTPSIP1CA12CA1CA2
Monoethanolamine SCHEMBL28529258 0.88 NAPRT (0.51) NAPRTPSIP1CA12CA1CA2
SCHEMBL23877120 0.86 NAPRT (0.53) NAPRTPSIP1CA12CA1CA2
SCHEMBL29297465 0.83 L3MBTL1 (0.50) NAPRTCA12CA1CA2CA9
SCHEMBL4688239 0.83 NAPRT (0.59) NAPRTCA12CA1CA2CA9
SCHEMBL27593133 0.82 NAPRT (0.45) NAPRTPSIP1CA12CA1CA2
SCHEMBL2376183 0.82 NAPRT (0.57) NAPRTCA12CA1CA2CA9
SCHEMBL28274755 0.82 NAPRT (0.57) NAPRTCA12CA1CA2CA9
SCHEMBL4688243 0.82 NAPRT (0.62) NAPRTCA12CA1CA2CA9
SCHEMBL24011092 0.81 NAPRT (0.52) NAPRTCA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12514251-B2 Fused heterocyclic compounds and their use as pest control agents PI INDUSTRIES LTD. (IN) 2026-01-06 US disclosed
EP-4613750-A1 HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD CONTROL COMPOSITION CONTAINING SAME Sumitomo Chemical Company, Limited (JP) 2025-09-10 EP disclosed
US-20240199600-A1 CONDENSED HETEROCYCLIC COMPOUND HAVING A SULFONAMIDE GROUP OR SALT THEREOF, AGRICULTURAL OR HORTICULTURAL INSECTICIDE OR ANIMAL ECTOPARASITE OR ENDOPARASITE CONTROL AGENT COMPRISING THE COMPOUND OR THE SALT THEREOF, AND METHOD FOR USING THE COMPOUND OR THE SALT THEREOF, THE INSECTICIDE, OR THE CONTROL AGENT NIHON NOHYAKU CO., LTD. (JP) 2024-06-20 US disclosed
WO-2024096093-A1 HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD CONTROL COMPOSITION CONTAINING SAME 住友化学株式会社 2024-05-10 WO disclosed
US-20230089381-A1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS PI INDUSTRIES LTD. (IN) 2023-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199600-A1 CONDENSED HETEROCYCLIC COMPOUND HAVING A SULFONAMIDE GROUP OR SALT THEREOF, AGRICULTURAL OR HORTICULTURAL INSECTICIDE OR ANIMAL ECTOPARASITE OR ENDOPARASITE CONTROL AGENT COMPRISING THE COMPOUND OR THE SALT THEREOF, AND METHOD FOR USING THE COMPOUND OR THE SALT THEREOF, THE INSECTICIDE, OR THE CONTROL AGENT HDAC2, HDAC1, HDAC11 NAPRT 585/4885PSIP1 127/4885CA12 998/4885
US-20230089381-A1 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS DDT, ACHE, CBR1 NAPRT 2353/4885PSIP1 1723/4885CA12 3402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.