Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF3 | O95398 | 5/20 | 0.66 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23832478 | 1.00 | RAPGEF3 (0.66) | RAPGEF3POLBTDP1KMT2AMEN1 | |
| SCHEMBL29045134 | 0.85 | RAPGEF3 (0.80) | RAPGEF3POLBKMT2AMEN1PPARG | |
| SCHEMBL23843539 | 0.83 | RAPGEF3 (0.85) | RAPGEF3POLBKMT2AMEN1PPARG | |
| SCHEMBL30199363 | 0.82 | RAPGEF3 (0.72) | RAPGEF3POLBKMT2AMEN1PPARG | |
| SCHEMBL23832474 | 0.82 | RAPGEF3 (0.72) | RAPGEF3POLBKMT2AMEN1PPARG | |
| SCHEMBL25179350 | 0.82 | RAPGEF3 (0.75) | RAPGEF3POLBTDP1KMT2AMEN1 | |
| SCHEMBL30200098 | 0.81 | RAPGEF3 (0.69) | RAPGEF3POLBTDP1KMT2AMEN1 | |
| SCHEMBL23832449 | 0.81 | RAPGEF3 (0.69) | RAPGEF3POLBTDP1KMT2AMEN1 | |
| SCHEMBL23843452 | 0.80 | RAPGEF3 (0.72) | RAPGEF3POLBTDP1KMT2AMEN1 | |
| SCHEMBL29843580 | 0.80 | RAPGEF3 (0.72) | RAPGEF3POLBTDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134015-A | Selective acyclic nucleotide activating factor for CAMP sensor EPAC1 | 得克萨斯州大学系统董事会 | 2023-05-16 | — | — | CN | disclosed |
| EP-4121411-A1 | SELECTIVE NON-CYCLIC NUCLEOTIDE ACTIVATORS FOR THE CAMP SENSOR EPAC1 | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-01-25 | — | — | EP | disclosed |