SCHEMBL29045134

SCHEMBL29045134

Cc1ccccc1S(=O)(=O)NC(=O)COc1ccc2ccccc2c1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF3 O95398 6/20 0.80
POLB P06746 6/20 0.57
RAB9A P51151 2/20 0.56
MEN1 O00255 6/20 0.56
KMT2A Q03164 6/20 0.56
CTDSP1 Q9GZU7 2/20 0.56
PPARG P37231 3/20 0.56
NCOA2 Q15596 3/20 0.56
NCOA1 Q15788 3/20 0.56
NCOA3 Q9Y6Q9 3/20 0.56
HTT P42858 2/20 0.56
NPSR1 Q6W5P4 1/20 0.56
NR2E3 Q9Y5X4 1/20 0.56
NCOR2 Q9Y618 1/20 0.56
HPGD P15428 1/20 0.51
RECQL P46063 1/20 0.51
ALDH1A1 P00352 1/20 0.51
MAPT P10636 1/20 0.51
BLM P54132 1/20 0.51
PTPN7 P35236 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25462255 0.88 RAPGEF3 (0.81) RAPGEF3POLBRAB9AMEN1KMT2A
SCHEMBL30199398 0.85 RAPGEF3 (0.66) RAPGEF3POLBRAB9AMEN1KMT2A
SCHEMBL23832478 0.85 RAPGEF3 (0.66) RAPGEF3POLBRAB9AMEN1KMT2A
SCHEMBL23843607 0.84 RAPGEF3 (0.75) RAPGEF3POLBRAB9AMEN1KMT2A
SCHEMBL30439501 0.84 RAPGEF3 (0.75) RAPGEF3POLBRAB9AMEN1KMT2A
SCHEMBL25462147 0.83 RAPGEF3 (0.89) RAPGEF3POLBRAB9AMEN1KMT2A
SCHEMBL23843539 0.83 RAPGEF3 (0.85) RAPGEF3POLBRAB9AMEN1KMT2A
SCHEMBL25173501 0.82 RAPGEF3 (0.76) RAPGEF3POLBRAB9AMEN1KMT2A
SCHEMBL23832448 0.82 RAPGEF3 (0.72) RAPGEF3POLBRAB9AMEN1KMT2A
SCHEMBL25462131 0.82 RAPGEF3 (0.89) RAPGEF3POLBRAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116134015-A Selective acyclic nucleotide activating factor for CAMP sensor EPAC1 得克萨斯州大学系统董事会 2023-05-16 CN disclosed