Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.40 |
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | GLP1R | P43220 | 3/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199079 | 0.84 | HRH3 (0.39) | HRH3HRH1GPR84 | |
| SCHEMBL30199782 | 0.83 | HRH3 (0.44) | HRH3HRH1GPR84 | |
| SCHEMBL30200138 | 0.82 | HRH3 (0.41) | HRH3HRH1MCHR1GPR84KCNH2 | |
| SCHEMBL30199307 | 0.82 | GLP1R (0.41) | GLP1R | |
| SCHEMBL30199309 | 0.81 | HRH3 (0.44) | HRH3HRH1GPR84 | |
| SCHEMBL30199470 | 0.81 | HRH3 (0.39) | HRH3HRH1GPR84 | |
| SCHEMBL30199641 | 0.81 | S1PR1 (0.34) | CXCR3DRD2HTR7 | |
| SCHEMBL30199664 | 0.81 | GPR84 (0.44) | HRH3HRH1GPR84 | |
| SCHEMBL30199409 | 0.81 | KCNH2 (0.41) | HRH3HRH1GPR84GLP1RKCNH2 | |
| SCHEMBL30199156 | 0.81 | KCNH2 (0.41) | HRH3HRH1GPR84GLP1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |