Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199267 | 0.90 | GPR84 (0.43) | HRH3CYP2D6HRH1S1PR5MCHR1 | |
| SCHEMBL30199745 | 0.88 | HRH3 (0.38) | HRH3CYP2D6HRH1S1PR5PRMT5 | |
| SCHEMBL30199647 | 0.88 | HRH3 (0.55) | HRH3CYP2D6HRH1PRMT5WDR77 | |
| SCHEMBL30199409 | 0.87 | KCNH2 (0.41) | HRH3HRH1KCNH2GPR84 | |
| SCHEMBL30199156 | 0.87 | KCNH2 (0.41) | HRH3HRH1KCNH2GPR84 | |
| SCHEMBL30199309 | 0.86 | HRH3 (0.44) | HRH3CYP2D6HRH1MAOBGPR84 | |
| SCHEMBL30199401 | 0.85 | F10 (0.40) | HRH3CYP2D6HRH1PRMT5WDR77 | |
| SCHEMBL30199079 | 0.85 | HRH3 (0.39) | HRH3CYP2D6HRH1MAOBS1PR5 | |
| SCHEMBL30199500 | 0.84 | GPR84 (0.44) | HRH3CYP2D6HRH1PRMT5WDR77 | |
| SCHEMBL30199470 | 0.84 | HRH3 (0.39) | HRH3CYP2D6HRH1S1PR5S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |