Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.38 |
| ▸ | PRKDC | P78527 | 2/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30199647 | 0.88 | HRH3 (0.55) | GPR84HRH3CYP2D6HRH1PRMT5 | |
| SCHEMBL30199465 | 0.86 | HRH3 (0.44) | GPR84F10HRH3CYP2D6HRH1 | |
| SCHEMBL30199401 | 0.85 | F10 (0.40) | GPR84F10HRH3CYP2D6HRH1 | |
| SCHEMBL30198777 | 0.85 | HRH3 (0.46) | GPR84HRH3CYP2D6HRH1PRMT5 | |
| SCHEMBL30199411 | 0.85 | HRH3 (0.46) | GPR84HRH3CYP2D6HRH1PRMT5 | |
| SCHEMBL30200138 | 0.84 | HRH3 (0.41) | GPR84HRH3CYP2D6HRH1PRMT5 | |
| SCHEMBL30199267 | 0.84 | GPR84 (0.43) | GPR84HRH3CYP2D6HRH1PRKDC | |
| SCHEMBL30199360 | 0.82 | HRH3 (0.44) | GPR84HRH3CYP2D6HRH1 | |
| SCHEMBL30199615 | 0.82 | HRH3 (0.44) | HRH3CYP2D6HRH1 | |
| SCHEMBL30199309 | 0.82 | HRH3 (0.44) | GPR84HRH3CYP2D6HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |